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ITGB1BP1 and EEF1A1
Data Source:
BioGRID
(two hybrid)
ITGB1BP1
EEF1A1
Description
integrin subunit beta 1 binding protein 1
eukaryotic translation elongation factor 1 alpha 1
Image
GO Annotations
Cellular Component
Ruffle
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Focal Adhesion
Membrane
Nuclear Body
Lamellipodium
Centriolar Satellite
Perinuclear Region Of Cytoplasm
Cell Periphery
Extracellular Region
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Cytosol
Eukaryotic Translation Elongation Factor 1 Complex
Plasma Membrane
Membrane
Cortical Actin Cytoskeleton
Ruffle Membrane
Secretory Granule Lumen
Extracellular Exosome
Cytoplasmic Side Of Lysosomal Membrane
Ficolin-1-rich Granule Lumen
Molecular Function
GDP-dissociation Inhibitor Activity
Integrin Binding
Protein Binding
TRNA Binding
RNA Binding
Translation Elongation Factor Activity
GTPase Activity
Protein Binding
Calmodulin Binding
GTP Binding
Kinase Binding
Protein Kinase Binding
Biological Process
Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration
Cell-matrix Adhesion
Notch Signaling Pathway
Integrin-mediated Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Endothelial Cell Migration
Negative Regulation Of Fibroblast Migration
Cell Migration
Cell Differentiation
Biomineral Tissue Development
Negative Regulation Of Protein Binding
Activation Of Protein Kinase B Activity
Integrin Activation
Regulation Of Cell Adhesion Mediated By Integrin
Tube Formation
Intracellular Signal Transduction
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Regulation Of GTPase Activity
Receptor Clustering
Cellular Response To Fibroblast Growth Factor Stimulus
Positive Regulation Of Notch Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Myoblast Migration
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Cell Division
Negative Regulation Of Focal Adhesion Assembly
Positive Regulation Of Protein Kinase B Signaling
Negative Regulation Of ERK1 And ERK2 Cascade
Protein Localization To Plasma Membrane
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Protein Targeting To Membrane
Negative Regulation Of Protein Targeting To Membrane
Blood Vessel Diameter Maintenance
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Regulation Of Integrin-mediated Signaling Pathway
Translation
Translational Elongation
Neutrophil Degranulation
Cellular Response To Epidermal Growth Factor Stimulus
Regulation Of D-erythro-sphingosine Kinase Activity
Regulation Of Chaperone-mediated Autophagy
Pathways
Eukaryotic Translation Elongation
Eukaryotic Translation Elongation
Peptide chain elongation
HSF1 activation
Neutrophil degranulation
Protein methylation
Chaperone Mediated Autophagy
Drugs
Zinc
Guanosine-5'-Diphosphate
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes
19 interacting genes:
APP
CAMK2A
CCDC33
DLD
EEF1A1
FAF1
FIGNL1
GSDME
ITGB1
KRIT1
LRP1
LRP2
LRP8
RHOH
SLC35F5
SMO
SMURF1
SMURF2
UTRN
130 interacting genes:
ABTB2
ACTB
ALPL
ANKRD24
ANXA7
APLP1
AQP2
ARIH2
AXIN1
BBS1
BBS2
BBS4
BRMS1
BTBD2
CASP2
CCDC130
CCL18
CDC25A
CDKN1A
CKS2
COX17
CRADD
CRCT1
CSRP2
DARS1
DIABLO
DLEU1
DUSP7
DYNLL1
DYSF
EIF3F
EP300
EXOSC4
FAS
GADD45A
GADD45G
HSPB2
HSPE1
HTRA2
IKBKG
IMMT
ITGB1BP1
ITSN1
KCNE3
KIF1B
LAMA4
LAMTOR1
LAMTOR5
LSM3
MAD2L1BP
MAGED2
MAP3K14
MAPK14
MLLT3
MNAT1
MRM1
MRPL42
MTRNR2L1
MYOC
NEU1
NRAS
NREP
ORMDL3
PABPC4
PAEP
PAFAH1B3
PAPSS1
PCDHA4
PFN2
PHYHIP
PKN2
PLAUR
PLCG1
POLE2
POLR2C
PQBP1
PRKCD
PSG9
PSMD11
PTPN4
PTPRCAP
PTPRF
RAB27A
RAP2A
RBBP8
RFC5
RGS12
RND1
RNF10
RPA2
RPLP1
RRAS
RSRC1
SARS2
SDHAF2
SERPINB5
SERPINB9
SFN
SHBG
SMAD2
SMAD4
SMN1
SNCA
SPP1
SSR1
STAT6
STMN2
SULT1E1
SUMO2
TAF9
TGIF1
TK1
TMPRSS3
TNFSF11
TP53BP2
TPT1
TRDMT1
TSPY1
TSPYL2
TTLL12
TTR
UBQLN4
WARS1
XPO5
XRN2
YWHAG
ZBTB16
ZCCHC10
ZNF24
ZPR1
Entrez ID
9270
1915
HPRD ID
06194
00559
Ensembl ID
ENSG00000119185
ENSG00000156508
Uniprot IDs
B4DQY5
O14713
P68104
Q6IPS9
PDB IDs
1K11
4DX8
4DX9
4JIF
1SYW
3C5J
6ZMO
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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