SLC16A7 and GPR25

Data Source:
BioGRID (two hybrid)

		SLC16A7	GPR25
Description		solute carrier family 16 member 7	G protein-coupled receptor 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Pyruvate Secondary Active Transmembrane Transporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Pyruvate Transmembrane Transporter Activity	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Monocarboxylic Acid Transport Lactate Transmembrane Transport Transport Across Blood-brain Barrier Pyruvate Transmembrane Transport	G Protein-coupled Receptor Signaling Pathway
Pathways		Proton-coupled monocarboxylate transport	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Pyruvic acid
Diseases
GWAS		Adventurousness ( 30643258) Calcium levels ( 25972035) General risk tolerance (MTAG) ( 30643258) Hematocrit ( 29403010) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Takayasu arteritis ( 25604533)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)
Interacting Genes		15 interacting genes: ACSL5 CDIPT COMT CPEB1 FXYD6 GPR25 HMOX1 IFITM3 LEMD1 SFXN1 SMAGP SNTA1 TIMM23 VAPA VTI1B	32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB
Entrez ID		9194	2848
HPRD ID		06791	03707
Ensembl ID		ENSG00000118596	ENSG00000170128
Uniprot IDs		A0A024RBB2 O60669	O00155
PDB IDs		7BP3
Enriched GO Terms of Interacting Partners?
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