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STX2 and PLN
Data Source:
BioGRID
(two hybrid)
STX2
PLN
Description
syntaxin 2
phospholamban
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
Synaptic Vesicle
Endomembrane System
Integral Component Of Membrane
Basolateral Plasma Membrane
Lamellipodium
SNARE Complex
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Presynaptic Active Zone Membrane
Mitochondrion
Endoplasmic Reticulum
Membrane
Mitochondrial Membrane
Vesicle
Sarcoplasmic Reticulum Membrane
Perinuclear Region Of Cytoplasm
Calcium Ion-transporting ATPase Complex
Molecular Function
SNARE Binding
Structural Molecule Activity
SNAP Receptor Activity
Protein Binding
Calcium-dependent Protein Binding
Enzyme Inhibitor Activity
Protein Binding
ATPase Inhibitor Activity
Identical Protein Binding
Protein Homodimerization Activity
ATPase Binding
Biological Process
Intracellular Protein Transport
Exocytosis
Vesicle Fusion
Signal Transduction
Acrosome Reaction
Ectoderm Development
Animal Organ Morphogenesis
Cell Differentiation
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Cellular Response To Oxidative Stress
Vesicle Docking
Cornified Envelope Assembly
Regulation Of The Force Of Heart Contraction
Calcium Ion Transport
Notch Signaling Pathway
Blood Circulation
Regulation Of Heart Contraction
Response To Zinc Ion
Negative Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Negative Regulation Of ATPase Activity
Response To Insulin
Response To Testosterone
Negative Regulation Of Catalytic Activity
Cardiac Muscle Tissue Development
Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Calcium Ion Transport
Negative Regulation Of Calcium Ion Transport
Relaxation Of Cardiac Muscle
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Cardiac Muscle Cell Contraction
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Regulation Of Cardiac Muscle Cell Membrane Potential
Regulation Of The Force Of Heart Contraction By Cardiac Conduction
Negative Regulation Of Calcium Ion Import
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Calcium Ion Binding
Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Regulation Of Relaxation Of Cardiac Muscle
Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways
Ion homeostasis
Ion transport by P-type ATPases
Drugs
Diseases
GWAS
Initial pursuit acceleration in psychotic disorders (
29064472
)
Metabolite levels (
23823483
)
Plasma plasminogen activator levels (
24578379
)
vWF levels (
30586737
)
Atrial fibrillation (
28416818
30061737
)
Cardiac structure and function (
19584346
)
QRS complex (Sokolow-Lyon) (
27659466
)
QRS duration (
27577874
27659466
)
QT interval (
23166209
24952745
19305408
19305409
19587794
29874175
)
Resting heart rate (
27798624
)
Interacting Genes
64 interacting genes:
AARD
ABI3
ANKRD46
APOL2
BET1
BLOC1S2
CD53
CDC23
CERT1
CPLX2
CTSA
CYBC1
EBAG9
ENTPD3
FGA
GET1
GIMAP5
MIP
MRPL11
MTG1
NAPB
NINJ2
PCGF2
PLN
PLPP4
RMDN3
RNF4
RTP2
SEC22A
SEC22B
SERP1
SLC18A1
SNAP25
SNAP29
STRIT1
STX12
STX16
STX1A
STX1B
STX3
STX4
STX5
STX6
STX7
STX8
STXBP1
STXBP2
STXBP5L
SYT1
SYT4
SYT7
TMEM120A
TMEM120B
TSPAN8
UBE2I
UNC13B
VAMP2
VAMP3
VAMP5
VAPB
VTI1B
ZCCHC12
ZFPL1
ZNF785
64 interacting genes:
ARL13B
ASGR2
ATP2A1
ATP2A2
ATP6V0E1
BCL2L13
BIK
CD53
CLDN7
CLEC2D
CPLX4
CREB3
CREB3L1
DMPK
DVL3
EDA
ELOVL4
FAM209A
FKBP8
FNDC9
GJA8
GPR152
GPR37L1
GPX8
HIBADH
HSD17B13
KIR2DL3
LDLRAD1
LSMEM2
MFF
MFSD5
MGST2
MGST3
MS4A7
MTIF3
MUC1
PLPPR1
PPP1R3A
PRKACA
RTN3
S100A1
SAR1A
SDC3
SIT1
SLC14A2
SLC30A8
SLC34A2
SLC35C2
SLC39A2
SLN
SPACA1
SPAG4
STX1A
STX2
TMEM106C
TMEM179B
TMEM205
TMEM31
TMEM45A
TMEM45B
TMEM52B
TMEM79
TMEM86B
TMPRSS2
Entrez ID
2054
5350
HPRD ID
11816
01395
Ensembl ID
ENSG00000111450
ENSG00000198523
Uniprot IDs
P32856
P26678
Q5R352
PDB IDs
1K9N
1KCH
1PLN
1PLP
1PSL
1ZLL
2HYN
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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