STX2 and STX12

Data Source:
BioGRID (two hybrid)

		STX2	STX12
Description		syntaxin 2	syntaxin 12
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane	Golgi Membrane Phagophore Assembly Site Nucleoplasm Golgi Apparatus Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Intracellular Membrane-bounded Organelle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Calcium-dependent Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Cell Differentiation Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization
Pathways
Drugs
Diseases
GWAS		Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)
Interacting Genes		64 interacting genes: AARD ABI3 ANKRD46 APOL2 BET1 BLOC1S2 CD53 CDC23 CERT1 CPLX2 CTSA CYBC1 EBAG9 ENTPD3 FGA GET1 GIMAP5 MIP MRPL11 MTG1 NAPB NINJ2 PCGF2 PLN PLPP4 RMDN3 RNF4 RTP2 SEC22A SEC22B SERP1 SLC18A1 SNAP25 SNAP29 STRIT1 STX12 STX16 STX1A STX1B STX3 STX4 STX5 STX6 STX7 STX8 STXBP1 STXBP2 STXBP5L SYT1 SYT4 SYT7 TMEM120A TMEM120B TSPAN8 UBE2I UNC13B VAMP2 VAMP3 VAMP5 VAPB VTI1B ZCCHC12 ZFPL1 ZNF785	43 interacting genes: AQP6 AQP8 BCL2L13 BLOC1S6 CD79A CISD2 DNAJC5 DTX2 EBP EEA1 EPB42 ERGIC3 FCER1G GORAB HOMER1 KASH5 LEPROTL1 LMNA MFSD6 MMGT1 NAPA NEMP1 NSG1 PDZK1IP1 PLPPR2 RIC3 SEC11C SLC10A6 SLC66A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STXBP5L TIMMDC1 TLCD4 TMEM14B TMEM167B TMEM31 TMEM86B TMX2
Entrez ID		2054	23673
HPRD ID		11816	06059
Ensembl ID		ENSG00000111450	ENSG00000117758
Uniprot IDs		P32856	Q86Y82
PDB IDs			2DNX
Enriched GO Terms of Interacting Partners?
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