SMC3 and SMC1B

Data Source:
HPRD (in vivo, in vitro)

		SMC3	SMC1B
Description		structural maintenance of chromosomes 3	structural maintenance of chromosomes 1B
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Lateral Element Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Meiotic Cohesin Complex Nuclear Meiotic Cohesin Complex Mitotic Spindle Pole	Chromosome, Centromeric Region Lateral Element Nucleus Nucleoplasm Cytosol Cohesin Complex Meiotic Cohesin Complex Nuclear Meiotic Cohesin Complex
	Molecular Function	Chromatin Binding Microtubule Motor Activity Protein Binding ATP Binding Mediator Complex Binding Protein Heterodimerization Activity Beta-tubulin Binding Dynein Complex Binding	DNA Binding ATP Binding
	Biological Process	Mitotic Cell Cycle Regulation Of DNA Replication DNA Repair Sister Chromatid Cohesion Stem Cell Population Maintenance Cell Division Meiotic Cell Cycle Mitotic Spindle Assembly	Sister Chromatid Cohesion Mitotic Sister Chromatid Cohesion Meiotic Cell Cycle
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression	Meiotic synapsis
Drugs
Diseases		Cornelia de Lange syndrome (CdLS)
GWAS		Acute respiratory distress syndrome in sepsis ( 31982041) Lumbar spine bone mineral density (integral) ( 27476799) Metabolite levels ( 23823483)	Height ( 28552196) Peanut allergy (maternal genetic effects) ( 29489655)
Interacting Genes		18 interacting genes: APC CEP63 DISC1 ESCO2 ESR1 FEZ1 FEZ2 KIFAP3 MTNR1B MXD1 MXD3 MXD4 MXI1 RPGR SMC1A SMC1B SUMO2 TRAF3IP1	1 interacting genes: SMC3
Entrez ID		9126	27127
HPRD ID		05829	10564
Ensembl ID		ENSG00000108055	ENSG00000077935
Uniprot IDs		Q9UQE7	Q8NDV3
PDB IDs		6WG3 6WG4 6WG6 6WGE
Enriched GO Terms of Interacting Partners?
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