NMI and MAD2L1BP

Data Source:
BioGRID (two hybrid)

		NMI	MAD2L1BP
Description		N-myc and STAT interactor	MAD2L1 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Spindle Nuclear Membrane
	Molecular Function	Transcription Coregulator Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Macrophage Activation Involved In Immune Response Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Interferon-gamma-mediated Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein K48-linked Ubiquitination	Regulation Of Exit From Mitosis Deactivation Of Mitotic Spindle Assembly Checkpoint
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		58 interacting genes: BRAT1 BRCA1 BRMS1 C1orf216 C9orf72 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EXOSC5 GCSH GOLGA8EP HDDC3 HGS HHLA3 HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I	21 interacting genes: ANAPC4 CDC20 CEP126 EEF1A1 FNDC8 HOMEZ IGSF21 INPP5K KAT5 KRT15 LRIF1 MAD2L1 MAD2L2 NMI PLK1 PTN SETDB1 TP53 TRIP13 ZBTB14 ZNF202
Entrez ID		9111	9587
HPRD ID		04632	10065
Ensembl ID		ENSG00000123609	ENSG00000124688
Uniprot IDs		Q13287	Q15013
PDB IDs			2QYF 6F0X
Enriched GO Terms of Interacting Partners?
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