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NMI and COPS7B
Data Source:
BioGRID
(two hybrid, two hybrid)
NMI
COPS7B
Description
N-myc and STAT interactor
COP9 signalosome subunit 7B
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Nucleoplasm
Cytosol
COP9 Signalosome
Molecular Function
Transcription Coregulator Activity
Protein Binding
Identical Protein Binding
Protein Binding
Biological Process
Macrophage Activation Involved In Immune Response
Regulation Of Transcription, DNA-templated
Transcription By RNA Polymerase II
Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Cell Population Proliferation
Response To Virus
Negative Regulation Of Interferon-alpha Production
Negative Regulation Of Interferon-beta Production
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Innate Immune Response
Negative Regulation Of Innate Immune Response
Positive Regulation Of Inflammatory Response
Interferon-gamma-mediated Signaling Pathway
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Protein K48-linked Ubiquitination
Protein Deneddylation
Nucleotide-excision Repair, DNA Damage Recognition
Transcription-coupled Nucleotide-excision Repair
COP9 Signalosome Assembly
Viral Process
Post-translational Protein Modification
Pathways
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation
Drugs
Diseases
GWAS
Blood protein levels (
28240269
)
Height (
18391951
)
Interacting Genes
58 interacting genes:
BRAT1
BRCA1
BRMS1
C1orf216
C9orf72
CDKN2A
CDKN2D
CNKSR3
CNOT7
COPS7B
CYP2E1
EMILIN1
EXOSC5
GCSH
GOLGA8EP
HDDC3
HGS
HHLA3
HOXC9
HSPA8
HSPH1
IFI35
KDM1A
LCA5L
LSM4
MAD2L1BP
MCPH1
MORF4L1
MTMR6
MTMR9
MYC
MYCN
MYOM3
NECAP2
POMZP3
PSMA1
RYBP
SCEL
SFR1
SH3GLB2
SINHCAF
SNAPC5
SOX10
STAT1
STAT3
STAT4
STAT5A
STAT5B
STAT6
THAP8
TRAF5
TRIM72
TRIP12
TUBA3C
TUBA3E
TXLNA
TXLNB
UBE2I
11 interacting genes:
APP
BEX5
COPS2
COPS3
COPS4
COPS5
COPS6
EIF3E
GPS1
NMI
PMF1
Entrez ID
9111
64708
HPRD ID
04632
09889
Ensembl ID
ENSG00000123609
ENSG00000144524
Uniprot IDs
Q13287
A0A024R471
A0A024R478
A0A087X1P5
J3KQ34
J3KQ41
Q6ZTQ7
Q9H9Q2
PDB IDs
6R6H
6R7F
6R7H
6R7I
6R7N
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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