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NMI and BRMS1
Data Source:
BioGRID
(two hybrid, two hybrid)
NMI
BRMS1
Description
N-myc and STAT interactor
BRMS1 transcriptional repressor and anoikis regulator
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Nucleus
Nucleoplasm
Cytoplasm
Sin3-type Complex
Molecular Function
Transcription Coregulator Activity
Protein Binding
Identical Protein Binding
Protein Binding
Histone Deacetylase Binding
NF-kappaB Binding
Biological Process
Macrophage Activation Involved In Immune Response
Regulation Of Transcription, DNA-templated
Transcription By RNA Polymerase II
Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Cell Population Proliferation
Response To Virus
Negative Regulation Of Interferon-alpha Production
Negative Regulation Of Interferon-beta Production
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Innate Immune Response
Negative Regulation Of Innate Immune Response
Positive Regulation Of Inflammatory Response
Interferon-gamma-mediated Signaling Pathway
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Protein K48-linked Ubiquitination
Negative Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Histone Deacetylation
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Apoptotic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Protein Deacetylation
Positive Regulation Of Anoikis
Pathways
HDACs deacetylate histones
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Blood protein levels (
28240269
)
Bipolar disorder (
21926972
31043756
)
Interacting Genes
58 interacting genes:
BRAT1
BRCA1
BRMS1
C1orf216
C9orf72
CDKN2A
CDKN2D
CNKSR3
CNOT7
COPS7B
CYP2E1
EMILIN1
EXOSC5
GCSH
GOLGA8EP
HDDC3
HGS
HHLA3
HOXC9
HSPA8
HSPH1
IFI35
KDM1A
LCA5L
LSM4
MAD2L1BP
MCPH1
MORF4L1
MTMR6
MTMR9
MYC
MYCN
MYOM3
NECAP2
POMZP3
PSMA1
RYBP
SCEL
SFR1
SH3GLB2
SINHCAF
SNAPC5
SOX10
STAT1
STAT3
STAT4
STAT5A
STAT5B
STAT6
THAP8
TRAF5
TRIM72
TRIP12
TUBA3C
TUBA3E
TXLNA
TXLNB
UBE2I
49 interacting genes:
ANGPTL4
APP
ARID4A
BEX2
BRMS1L
CEP70
CSNK2A1
CYTOR
DIRAS3
DNAJB1
DNAJB6
E2F1
EEF1A1
EP300
GOLGB1
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC6
HSP90AA1
HSPA4
IL13RA2
ING1
KLK9
KPNA5
LRIF1
LYPD3
MCRS1
MRC2
NMI
PFDN5
PSMC3IP
RBBP4
RBBP7
RBP1
RELA
SAP30
SIN3A
SMARCE1
SMTN
SNAI1
SNX6
SPOP
SUDS3
TAF1
THRSP
UBE2D1
Entrez ID
9111
25855
HPRD ID
04632
05879
Ensembl ID
ENSG00000123609
ENSG00000174744
Uniprot IDs
Q13287
G5E9I4
Q9HCU9
PDB IDs
2XUS
4AUV
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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