BRMS1 and LYPD3

Data Source:
BioGRID (two hybrid)

		BRMS1	LYPD3
Description		BRMS1 transcriptional repressor and anoikis regulator	LY6/PLAUR domain containing 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane
	Molecular Function	Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Laminin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Cell-matrix Adhesion
Pathways		HDACs deacetylate histones Potential therapeutics for SARS	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Cotinine glucuronidation ( 25293881)
Interacting Genes		49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11
Entrez ID		25855	27076
HPRD ID		05879	10783
Ensembl ID		ENSG00000174744	ENSG00000124466
Uniprot IDs		G5E9I4 Q9HCU9	B2RBR3 O95274
PDB IDs		2XUS 4AUV	6IOM 6ION
Enriched GO Terms of Interacting Partners?
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