SEC11C and TMEM42

Data Source:
BioGRID (two hybrid)

		SEC11C	TMEM42
Description		SEC11 homolog C, signal peptidase complex subunit	transmembrane protein 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity	Protein Binding
	Biological Process	Signal Peptide Processing
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Alzheimer's disease (age of onset) ( 22005931) Chronotype ( 30696823) Morning person ( 30696823)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756)
Interacting Genes		23 interacting genes: BTN2A2 C2 CADM3 GLP1R HMOX1 MFF PLPP6 PRSS23 RTP2 SCD SELENOM SERP1 STX12 TMEM128 TMEM243 TMEM254 TMEM42 TREX1 TSNARE1 UBE2J1 VAMP1 VAMP4 VAPA	54 interacting genes: AQP3 AQP6 BDKRB1 CD79A DTX2 EBP EDA ELOVL4 ERGIC3 FAM174A FAM209A GET1 GJA8 GOLM2 GPR152 GPX8 HSD17B11 HSD17B13 LEPROTL1 LHFPL5 LMNA MFF MGAT5B MMD MMGT1 MRM1 MTIF3 NEMP1 PROP1 PSCA RABAC1 RBPMS REEP1 REEP2 RETREG3 RHBDD1 SAR1A SCN3B SEC11C SERINC2 SHISAL1 SLC18A1 SLC34A2 SMIM14 SVOPL TLX3 TM4SF19 TMEM147 TMEM14B TMEM237 TMEM35A TMEM74 VENTX ZDHHC15
Entrez ID		90701	131616
HPRD ID		15310	15540
Ensembl ID		ENSG00000166562	ENSG00000169964
Uniprot IDs		K7EJQ7 Q9BY50	Q69YG0
PDB IDs
Enriched GO Terms of Interacting Partners?
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