SEC11C and CADM3

Data Source:
BioGRID (two hybrid)

		SEC11C	CADM3
Description		SEC11 homolog C, signal peptidase complex subunit	cell adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Cell-cell Junction Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	Signal Peptide Processing	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin	Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases
GWAS		Alzheimer's disease (age of onset) ( 22005931) Chronotype ( 30696823) Morning person ( 30696823)	Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 32296059) Bipolar disorder and eating disorder ( 26433762) Inflammatory biomarkers ( 22291609) Neutrophil count in HIV-infection ( 25884002)
Interacting Genes		23 interacting genes: BTN2A2 C2 CADM3 GLP1R HMOX1 MFF PLPP6 PRSS23 RTP2 SCD SELENOM SERP1 STX12 TMEM128 TMEM243 TMEM254 TMEM42 TREX1 TSNARE1 UBE2J1 VAMP1 VAMP4 VAPA	1 interacting genes: SEC11C
Entrez ID		90701	57863
HPRD ID		15310	13733
Ensembl ID		ENSG00000166562	ENSG00000162706
Uniprot IDs		K7EJQ7 Q9BY50	Q8N126
PDB IDs			1Z9M
Enriched GO Terms of Interacting Partners?
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