PSTPIP1 and LIN37

Data Source:
BioGRID (two hybrid)

		PSTPIP1	LIN37
Description		proline-serine-threonine phosphatase interacting protein 1	lin-37 DREAM MuvB core complex component
Image			No pdb structure
GO Annotations	Cellular Component	Uropod Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm	Nucleoplasm Transcription Repressor Complex Myb Complex
	Molecular Function	Protein Binding Identical Protein Binding Actin Filament Binding	Protein Binding
	Biological Process	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Actin Filament Polymerization Innate Immune Response	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection	Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases		Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)	Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)
Interacting Genes		64 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688	18 interacting genes: CCNDBP1 CDR2 CEP70 KIFC3 KRT31 KRT40 LZTS2 MAGEA6 MEOX2 PDE4DIP PNMA1 PSTPIP1 RBBP4 TEX11 TFIP11 TRAF1 TRIM54 ZNF76
Entrez ID		9051	55957
HPRD ID		05891	16872
Ensembl ID		ENSG00000140368	ENSG00000267796
Uniprot IDs		A0A0S2Z5P3 O43586	Q96GY3
PDB IDs		2DIL
Enriched GO Terms of Interacting Partners?
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