LIN37 and TEX11

Data Source:
HPRD (two hybrid)

		LIN37	TEX11
Description		lin-37 DREAM MuvB core complex component	testis expressed 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Repressor Complex Myb Complex	Synaptonemal Complex Central Element Chromosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Gonad Development Fertilization Negative Regulation Of Apoptotic Process Chiasma Assembly
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)	Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)
Interacting Genes		18 interacting genes: CCNDBP1 CDR2 CEP70 KIFC3 KRT31 KRT40 LZTS2 MAGEA6 MEOX2 PDE4DIP PNMA1 PSTPIP1 RBBP4 TEX11 TFIP11 TRAF1 TRIM54 ZNF76	91 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L C10orf82 C2CD6 C6orf226 CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414
Entrez ID		55957	56159
HPRD ID		16872	02256
Ensembl ID		ENSG00000267796	ENSG00000120498
Uniprot IDs		Q96GY3	Q8IYF3
PDB IDs
Enriched GO Terms of Interacting Partners?
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