PSTPIP1 and ZNF580

Data Source:
BioGRID (two hybrid)

		PSTPIP1	ZNF580
Description		proline-serine-threonine phosphatase interacting protein 1	zinc finger protein 580
Image			No pdb structure
GO Annotations	Cellular Component	Uropod Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding Actin Filament Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Actin Filament Polymerization Innate Immune Response	Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Leukocyte Chemotaxis Regulation Of Transcription By RNA Polymerase II Chemotaxis Inflammatory Response Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Positive Regulation Of Interleukin-8 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Hydrogen Peroxide
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases		Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		64 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688	27 interacting genes: ARHGEF6 BANP CCDC136 CYSRT1 FSD2 GOLGA6L9 HOMEZ IKZF1 KHDRBS3 KRT27 KRT34 KRT40 KRTAP10-7 KRTAP10-8 MDFI MTUS2 NBPF19 NOTCH2NLA PAX9 PSTPIP1 RAD54B SH3GL2 TRIM27 TRIP6 TSC22D4 XBP1 ZNF436
Entrez ID		9051	51157
HPRD ID		05891	18353
Ensembl ID		ENSG00000140368	ENSG00000213015
Uniprot IDs		A0A0S2Z5P3 O43586	Q9UK33
PDB IDs		2DIL
Enriched GO Terms of Interacting Partners?
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