ATP6V1E2 and ATP6V1G2

Data Source:
BioGRID (two hybrid)

		ATP6V1E2	ATP6V1G2
Description		ATPase H+ transporting V1 subunit E2	ATPase H+ transporting V1 subunit G2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytosol Proton-transporting Two-sector ATPase Complex, Catalytic Domain	Cytosol Vacuolar Proton-transporting V-type ATPase Complex Melanosome
	Molecular Function	Protein Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding ATPase-coupled Transmembrane Transporter Activity
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid	Tiludronic acid
Diseases
GWAS		Anti-saccade error rate in psychotic disorders ( 29064472) Anti-saccade response ( 29064472) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) LDL cholesterol levels ( 32203549) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Myositis ( 26291516) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: ATP6V1G1 ATP6V1G2 BBLN MESD RASSF10	3 interacting genes: ATP6V1E1 ATP6V1E2 USP20
Entrez ID		90423	534
HPRD ID		16525	06030
Ensembl ID		ENSG00000250565	ENSG00000213760
Uniprot IDs		A0A140VKA8 Q96A05	O95670 Q6NVJ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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