ATP6V1E2 and ATP6V1G1

Data Source:
BioGRID (two hybrid, two hybrid, proximity labelling technology)

		ATP6V1E2	ATP6V1G1
Description		ATPase H+ transporting V1 subunit E2	ATPase H+ transporting V1 subunit G1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytosol Proton-transporting Two-sector ATPase Complex, Catalytic Domain	Lysosomal Membrane Cytosol Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Protein Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding ATPase Activity Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid	Tiludronic acid
Diseases
GWAS		Anti-saccade error rate in psychotic disorders ( 29064472) Anti-saccade response ( 29064472) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Bone mineral density (hip) and age at menarche ( 26312577) Bone mineral density (spine) and age at menarche ( 26312577)
Interacting Genes		5 interacting genes: ATP6V1G1 ATP6V1G2 BBLN MESD RASSF10	13 interacting genes: AP2B1 APP ATP6V1E1 ATP6V1E2 BCL2L11 GOLGA2 GOLGA6L9 GORASP2 LDOC1 LHX3 MAGEA6 NTAQ1 PNMA1
Entrez ID		90423	9550
HPRD ID		16525	06294
Ensembl ID		ENSG00000250565	ENSG00000136888
Uniprot IDs		A0A140VKA8 Q96A05	A0A024R883 O75348
PDB IDs
Enriched GO Terms of Interacting Partners?
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