PRPF4B and POLR3F

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		PRPF4B	POLR3F
Description		pre-mRNA processing factor 4B	RNA polymerase III subunit F
Image
GO Annotations	Cellular Component	Nucleus Chromosome Nuclear Speck Catalytic Step 2 Spliceosome	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	RNA Binding Protein Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Double-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Phosphorylation RNA Splicing MRNA Cis Splicing, Via Spliceosome	Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways			Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs		Fostamatinib
Diseases
GWAS		Night sleep phenotypes ( 27126917)	Refractive error ( 32231278)
Interacting Genes		8 interacting genes: CLK1 HSPB3 KLF13 PNN POLR3F SRPK2 SRSF1 YWHAG	15 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 PRPF4B RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89
Entrez ID		8899	10621
HPRD ID		09087	15156
Ensembl ID		ENSG00000112739	ENSG00000132664
Uniprot IDs		A0A024QZY5 Q13523	Q05DB8 Q9H1D9
PDB IDs		4IAN 4IFC 4IIR 4IJP 6CNH 6PJJ 6PK6 6QX9	2DK5 2YU3
Enriched GO Terms of Interacting Partners?
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