PRPF4B and KLF13

Data Source:
HPRD (in vivo, two hybrid)

		PRPF4B	KLF13
Description		pre-mRNA processing factor 4B	Kruppel like factor 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Nuclear Speck Catalytic Step 2 Spliceosome	Chromatin Nucleus
	Molecular Function	RNA Binding Protein Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Phosphorylation RNA Splicing MRNA Cis Splicing, Via Spliceosome	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Night sleep phenotypes ( 27126917)	Brain volume in infants (intracranial brain volume) ( 28763065) Deep white matter hyperintensities ( 32517579) Eosinophilic esophagitis ( 25017104) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494) Psoriasis ( 28537254) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triglyceride levels ( 32203549) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		8 interacting genes: CLK1 HSPB3 KLF13 PNN POLR3F SRPK2 SRSF1 YWHAG	9 interacting genes: CREBBP EP300 KAT2B PCBD1 PRPF4B SERPINH1 SIN3A SREBF1 SREBF2
Entrez ID		8899	51621
HPRD ID		09087	05620
Ensembl ID		ENSG00000112739	ENSG00000169926
Uniprot IDs		A0A024QZY5 Q13523	Q9Y2Y9 X5DNR2
PDB IDs		4IAN 4IFC 4IIR 4IJP 6CNH 6PJJ 6PK6 6QX9
Enriched GO Terms of Interacting Partners?
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