SUCLA2 and TNFRSF10D

Data Source:
BioGRID (two hybrid)

		SUCLA2	TNFRSF10D
Description		succinate-CoA ligase ADP-forming subunit beta	TNF receptor superfamily member 10d
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex Extracellular Exosome	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding
	Biological Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinyl-CoA Pathway	Apoptotic Process Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Leukocyte Migration
Pathways		Citric acid cycle (TCA cycle)	Cell surface interactions at the vascular wall TP53 Regulates Transcription of Death Receptors and Ligands TRAIL signaling
Drugs
Diseases		Mitochondrial DNA depletion syndrome (MDS)
GWAS		Aging (time to event) ( 21782286) Colorectal cancer (diet interaction) ( 24743840) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Attention deficit hyperactivity disorder ( 20732625) Lymphocyte percentage of white cells ( 32888494)
Interacting Genes		11 interacting genes: AGTRAP ALAS2 ARL6IP1 CMTM5 FAM9B FKBP7 MAGEA11 MAL2 MTNR1A SEC23A TNFRSF10D	28 interacting genes: APOL3 ARFIP1 CIAO2A ECPAS FAM114A1 GAD2 HSBP1L1 INPP5K LAT MIEF1 MTERF4 PCYT1A PITPNC1 PLPP6 POLL RBP1 RMDN2 SEMA4G SENP2 SLC39A7 SUCLA2 TARS2 TBRG4 THAP4 TNFRSF10A TNFRSF10B TNFSF10 TUFM
Entrez ID		8803	8793
HPRD ID		06798	04682
Ensembl ID		ENSG00000136143	ENSG00000173530
Uniprot IDs		E5KS60 Q9P2R7 Q9Y4T0	Q9UBN6
PDB IDs		6G4Q
Enriched GO Terms of Interacting Partners?
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