SUCLA2 and FKBP7

Data Source:
BioGRID (two hybrid)

		SUCLA2	FKBP7
Description		succinate-CoA ligase ADP-forming subunit beta	FKBP prolyl isomerase 7
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding
	Biological Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinyl-CoA Pathway	Protein Peptidyl-prolyl Isomerization Peptidyl-proline Modification
Pathways		Citric acid cycle (TCA cycle)
Drugs
Diseases		Mitochondrial DNA depletion syndrome (MDS)
GWAS		Aging (time to event) ( 21782286) Colorectal cancer (diet interaction) ( 24743840) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Atrial fibrillation ( 30061737) Blood protein levels ( 30072576 29875488) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: AGTRAP ALAS2 ARL6IP1 CMTM5 FAM9B FKBP7 MAGEA11 MAL2 MTNR1A SEC23A TNFRSF10D	76 interacting genes: ABHD16A ADIPOQ AP1M1 APOD ASPH BMP10 BRICD5 CDIPT CERCAM CIAO2A CLCA4 CLDN19 CTSA CXCL16 DIABLO FAM3C FARS2 GET3 H4C7 HHATL HSBP1L1 IER3 IFITM3 IRF2 JOSD2 LAT MAN2B2 MIEF2 MRM1 NFU1 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PEX19 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RPRM RUSF1 SGTA SLC38A7 SLC7A14 SNX1 SNX12 STX7 STX8 SUCLA2 TARS2 TCP11X2 THAP4 THSD7B TMEM108 TMEM120B TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TTPA TXNDC12 UBIAD1 UBQLN4 UPK1B VSTM4 WFDC2 WIPI2 YIPF6 ZFPL1
Entrez ID		8803	51661
HPRD ID		06798	08451
Ensembl ID		ENSG00000136143	ENSG00000079150
Uniprot IDs		E5KS60 Q9P2R7 Q9Y4T0	Q9Y680
PDB IDs		6G4Q
Enriched GO Terms of Interacting Partners?
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