TNFRSF10D and SUCLA2

Data Source:
BioGRID (two hybrid)

		TNFRSF10D	SUCLA2
Description		TNF receptor superfamily member 10d	succinate-CoA ligase ADP-forming subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding
	Biological Process	Apoptotic Process Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Leukocyte Migration	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinyl-CoA Pathway
Pathways		Cell surface interactions at the vascular wall TP53 Regulates Transcription of Death Receptors and Ligands TRAIL signaling	Citric acid cycle (TCA cycle)
Drugs
Diseases			Mitochondrial DNA depletion syndrome (MDS)
GWAS		Attention deficit hyperactivity disorder ( 20732625) Lymphocyte percentage of white cells ( 32888494)	Aging (time to event) ( 21782286) Colorectal cancer (diet interaction) ( 24743840) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		28 interacting genes: APOL3 ARFIP1 CIAO2A ECPAS FAM114A1 GAD2 HSBP1L1 INPP5K LAT MIEF1 MTERF4 PCYT1A PITPNC1 PLPP6 POLL RBP1 RMDN2 SEMA4G SENP2 SLC39A7 SUCLA2 TARS2 TBRG4 THAP4 TNFRSF10A TNFRSF10B TNFSF10 TUFM	11 interacting genes: AGTRAP ALAS2 ARL6IP1 CMTM5 FAM9B FKBP7 MAGEA11 MAL2 MTNR1A SEC23A TNFRSF10D
Entrez ID		8793	8803
HPRD ID		04682	06798
Ensembl ID		ENSG00000173530	ENSG00000136143
Uniprot IDs		Q9UBN6	E5KS60 Q9P2R7 Q9Y4T0
PDB IDs			6G4Q
Enriched GO Terms of Interacting Partners?
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