ADAM9 and SH3D19

Data Source:
HPRD (in vivo)

		ADAM9	SH3D19
Description		ADAM metallopeptidase domain 9	SH3 domain containing 19
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Focal Adhesion Cell Surface Integral Component Of Membrane Intrinsic Component Of External Side Of Plasma Membrane Extracellular Exosome	Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Metalloendopeptidase Activity Protein Kinase C Binding Integrin Binding Protein Binding Collagen Binding Metallopeptidase Activity SH3 Domain Binding Laminin Binding Metal Ion Binding	Protein Binding
	Biological Process	Activation Of MAPKK Activity Membrane Protein Ectodomain Proteolysis Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Response To Manganese Ion Cell Migration Keratinocyte Differentiation Positive Regulation Of Cell Migration Membrane Protein Intracellular Domain Proteolysis Cell Adhesion Mediated By Integrin Positive Regulation Of Cell Adhesion Mediated By Integrin Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Macrophage Fusion Response To Tumor Necrosis Factor Monocyte Activation Response To Hydrogen Peroxide Positive Regulation Of Protein Secretion Positive Regulation Of Membrane Protein Ectodomain Proteolysis Response To Glucocorticoid Positive Regulation Of Keratinocyte Migration Response To Calcium Ion Cellular Response To Lipopolysaccharide	Cytoskeleton Organization Regulation Of Cell Morphogenesis Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Pathways		Collagen degradation	Golgi Associated Vesicle Biogenesis
Drugs		INCB7839
Diseases		Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Basophil count ( 32888494)
Interacting Genes		9 interacting genes: ITGA3 ITGA6 ITGAV MAD2L2 PRKCD SH3D19 SH3GLB1 SNX9 TNF	12 interacting genes: ADAM10 ADAM12 ADAM15 ADAM17 ADAM9 CDC42 GRB2 SH3GL1 SH3GL3 SH3RF1 SH3YL1 SOS2
Entrez ID		8754	152503
HPRD ID		04091	16364
Ensembl ID		ENSG00000168615	ENSG00000109686
Uniprot IDs		Q13443	A0A494C1M0 Q5HYK7
PDB IDs		1M1V
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?