SH3D19 and SH3GL1

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SH3D19	SH3GL1
Description		SH3 domain containing 19	SH3 domain containing GRB2 like 1, endophilin A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane	Podosome Cytoplasm Cytosol Early Endosome Membrane Cell Projection Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynapse Glutamatergic Synapse Postsynaptic Density, Intracellular Component
	Molecular Function	Protein Binding	Protein Binding Protein C-terminus Binding Lipid Binding SH3 Domain Binding Phosphatase Binding Beta-1 Adrenergic Receptor Binding Identical Protein Binding Ion Channel Binding Cadherin Binding GTPase Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Morphogenesis Positive Regulation Of Membrane Protein Ectodomain Proteolysis	Signal Transduction Central Nervous System Development Synaptic Vesicle Uncoating Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Endocytosis
Pathways		Golgi Associated Vesicle Biogenesis	EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell
Drugs
Diseases
GWAS			Hematocrit ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		12 interacting genes: ADAM10 ADAM12 ADAM15 ADAM17 ADAM9 CDC42 GRB2 SH3GL1 SH3GL3 SH3RF1 SH3YL1 SOS2	37 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PRR5-ARHGAP8 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 SYNJ1 VIM VPS37C YWHAZ
Entrez ID		152503	6455
HPRD ID		16364	03462
Ensembl ID		ENSG00000109686	ENSG00000141985
Uniprot IDs		A0A494C1M0 Q5HYK7	Q6FGM0 Q99961
PDB IDs
Enriched GO Terms of Interacting Partners?
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