KRT38 and KRT8

Data Source:
BioGRID (two hybrid, two hybrid)

		KRT38	KRT8
Description		keratin 38	keratin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding
	Biological Process	Keratinization Cornification	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs			Tenecteplase Lanoteplase Copper
Diseases
GWAS			Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Mean reticulocyte volume ( 32888494) Prostate cancer ( 21743057)
Interacting Genes		72 interacting genes: - ABI3 AMOTL2 ANKRD36BP1 BEX2 BRME1 C1orf216 CCDC120 CCDC146 CD300A CEP57L1 DMRT3 DTNB FAM110A FAM90A1 GLRX3 GNG10 GNG13 HAUS1 HDAC4 HGS HMG20B HOXA1 HSF4 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LHX4 LMO3 LMO4 MAGEB4 MAPKBP1 PIK3R2 PIN1 POU4F2 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 SMARCD1 TBC1D21 TRIML2 TXLNA TXLNB TXNDC5 USHBP1 UTP23 ZFYVE21 ZNF20 ZNF417 ZNF587	49 interacting genes: ANXA1 BYSL CEP57 CLK1 DEDD DMD EGFR ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT38 KRT40 LINC01554 MAPK1 MAPK14 MAPK3 MAPK8 NEK6 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO2 TCHP TFIP11 TRIM54 TROAP WBP2
Entrez ID		8687	3856
HPRD ID		05176	01015
Ensembl ID		ENSG00000171360	ENSG00000170421
Uniprot IDs		O76015	P05787 Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners?
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