KRT8 and KRT13

Data Source:
BioGRID (two hybrid)

		KRT8	KRT13
Description		keratin 8	keratin 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Nucleus Cytosol Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Cytoskeleton Organization Keratinization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Tenecteplase Lanoteplase Copper
Diseases			White sponge nevus
GWAS		Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Mean reticulocyte volume ( 32888494) Prostate cancer ( 21743057)
Interacting Genes		49 interacting genes: ANXA1 BYSL CEP57 CLK1 DEDD DMD EGFR ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT38 KRT40 LINC01554 MAPK1 MAPK14 MAPK3 MAPK8 NEK6 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO2 TCHP TFIP11 TRIM54 TROAP WBP2	63 interacting genes: ABI2 ABI3 AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf109 C1orf216 C2CD6 CCHCR1 CCNC CEP57 CEP57L1 DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT4 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT79 KRT8 LSM2 MOS MYH1 MYO15B NEFL PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688
Entrez ID		3856	3860
HPRD ID		01015	01016
Ensembl ID		ENSG00000170421	ENSG00000171401
Uniprot IDs		P05787 Q7L4M3	A1A4E9 P13646
PDB IDs
Enriched GO Terms of Interacting Partners?
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