KRT8 and TROAP

Data Source:
BioGRID (pull down)

		KRT8	TROAP
Description		keratin 8	trophinin associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Cytoplasm
	Molecular Function	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding	Protein Binding
	Biological Process	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Cell Adhesion
Pathways		Keratinization Formation of the cornified envelope
Drugs		Tenecteplase Lanoteplase Copper
Diseases
GWAS		Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Mean reticulocyte volume ( 32888494) Prostate cancer ( 21743057)
Interacting Genes		49 interacting genes: ANXA1 BYSL CEP57 CLK1 DEDD DMD EGFR ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT38 KRT40 LINC01554 MAPK1 MAPK14 MAPK3 MAPK8 NEK6 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO2 TCHP TFIP11 TRIM54 TROAP WBP2	20 interacting genes: BANP BYSL C19orf54 DYNLT1 DYRK1A DYRK1B GIGYF1 KRT31 KRT40 KRT8 MAPRE1 MAPRE3 NBPF19 NOTCH2NLA OIP5 SSC4D TP53BP2 TRAF2 TRIM23 TRO
Entrez ID		3856	10024
HPRD ID		01015	04849
Ensembl ID		ENSG00000170421	ENSG00000135451
Uniprot IDs		P05787 Q7L4M3	F8W130 Q12815
PDB IDs
Enriched GO Terms of Interacting Partners?
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