KRT8 and KRT24

Data Source:
BioGRID (two hybrid)

		KRT8	KRT24
Description		keratin 8	keratin 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding	Molecular_function Structural Molecule Activity Protein Binding
	Biological Process	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Biological_process Keratinization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Tenecteplase Lanoteplase Copper
Diseases
GWAS		Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Mean reticulocyte volume ( 32888494) Prostate cancer ( 21743057)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 30929738 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		49 interacting genes: ANXA1 BYSL CEP57 CLK1 DEDD DMD EGFR ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT38 KRT40 LINC01554 MAPK1 MAPK14 MAPK3 MAPK8 NEK6 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO2 TCHP TFIP11 TRIM54 TROAP WBP2	32 interacting genes: AARD ABI2 ABI3 AMOT BFSP2 C1orf109 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT20 KRT3 KRT4 KRT5 KRT6C KRT71 KRT72 KRT75 KRT79 KRT8 KRT80 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA
Entrez ID		3856	192666
HPRD ID		01015	09668
Ensembl ID		ENSG00000170421	ENSG00000167916
Uniprot IDs		P05787 Q7L4M3	Q2M2I5
PDB IDs
Enriched GO Terms of Interacting Partners?
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