Description |
tankyrase |
DISC1 scaffold protein |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Acne (severe) ( 24927181)
- Bipolar disorder ( 31043756)
- Bone mineral density (Ward's triangle area) ( 27397699)
- Brain morphology (MOSTest) ( 32665545)
- Cataracts (operation) ( 31816047)
- Deep white matter hyperintensities ( 32517579)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
- Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
- Fish- and plant-related diet ( 32066663)
- General risk tolerance (MTAG) ( 30643258)
- Joint mobility (Beighton score) ( 27182965)
- LDL cholesterol levels ( 32203549)
- Metabolite levels ( 22916037)
- Mosquito bite size ( 28199695)
- Nose size ( 27182965)
- Obesity (early onset extreme) ( 20421936)
- Oily fish consumption ( 32066663)
- Pork consumption ( 32066663)
- Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
- Refractive error ( 32231278)
- Regular attendance at a religious group ( 29970889)
- Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
- Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578)
- Schizophrenia ( 26198764)
- Systemic lupus erythematosus ( 28714469)
- Systolic blood pressure ( 30224653)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
- Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
- Triglyceride levels ( 32154731)
- Type 2 diabetes ( 30054458)
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- Alzheimer's disease ( 19118814)
- Amyotrophic lateral sclerosis ( 19451621)
- Amyotrophic lateral sclerosis (sporadic) ( 24529757)
- Arterial stiffness index ( 31235810)
- Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451)
- Metabolite levels ( 23823483)
- Neuranatomic and neurocognitive phenotypes ( 21483430)
- Pelvic organ prolapse (moderate/severe) ( 26545240)
- Response to antidepressants (symptom improvement) ( 29160301)
- Response to antineoplastic agents ( 21659360)
- Response to statin therapy ( 20339536)
- Serum docosahexaenoic fatty acid concentration in metabolic syndrome ( 31991592)
- Waist circumference ( 28552196)
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Interacting Genes |
25 interacting genes:
ADPRS
ANKRD28
BABAM1
DISC1
EIF4A1
EPM2AIP1
FANCD2
FNBP1
LNPEP
MCL1
NELFE
NUMA1
OARD1
POT1
PTEN
SDCBP
SH3BP5
TCL1A
TERF1
TNIK
TNKS1BP1
TNKS2
UBASH3B
USP25
VPS33A
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188 interacting genes:
ABI2
ACTG1
ACTN2
ADO
AGTPBP1
AIMP2
AKAP6
AMOT
AP1M1
ARIH2
ARMC7
ATF4
ATF5
ATF7IP
BAG2
BFSP2
BICD1
BORCS6
BRD1
C1orf109
C2CD6
C8orf33
CARD9
CCDC102B
CCDC13
CCDC136
CCDC141
CCDC197
CCDC24
CCDC57
CCDC88A
CCDC92
CCHCR1
CDC23
CDC37
CDC5L
CDK5RAP3
CDKL3
CEP126
CEP57
CEP57L1
CEP63
CFAP206
CIT
CLU
COL4A1
CTNNA3
CWF19L2
DCTN1
DCTN2
DDX6
DMD
DNAJC7
DPYSL2
DPYSL3
DST
DYNC1H1
EEF2
EIF3H
EIF4A3
EMSY
EXOC1
EXOC4
EXOC7
FBXO34
FBXO41
FBXW7
FEZ1
FLACC1
FRYL
GABARAPL1
GAS2L2
GAS8
GCC1
GEM
GNB1
GNG13
GNPTAB
GPANK1
GPRASP2
GRIPAP1
GSK3B
HERC2P2
HNRNPC
IFT20
IFT74
IMMT
ITSN1
KALRN
KANSL1
KCNQ5
KIF3A
KIF3C
KIF9
KIFAP3
KIFC3
LENG1
MACF1
MAP1A
MEMO1
MLLT10
MNS1
MORF4L2
MPPED1
MVP
MYH7
MYT1L
NCK2
NDE1
NDEL1
NECAB1
NEFM
NME7
NSRP1
NUP160
OLFM1
PCNT
PCNX4
PDE4B
PGK1
PHF1
PIBF1
PIK3R3
PKN1
POLR3C
PPFIA3
PPM1E
PPP4R1
PPP5C
PSPC1
QARS1
RABGAP1
RAD21
RANBP9
RASSF7
RBM41
RBSN
RECK
RNF40
ROGDI
RTRAF
SH3BP5
SMARCD1
SMARCE1
SMC2
SMC3
SMC5
SMYD1
SNX6
SPARCL1
SPATC1L
SPTBN4
SRGAP2
SRGAP3
STX11
STX18
SUFU
SYBU
SYNE1
TCAF1
TCEANC
TFIP11
TIAM2
TNKS
TRAF3IP1
TRAF4
TRIM29
TRIM68
TRIO
TSGA10
TSPOAP1
TSR2
TTC23
TUBB
TUBB2A
UBASH3A
UBASH3B
USP2
UTRN
XPNPEP1
YWHAE
YWHAG
YWHAQ
YWHAZ
ZNF124
ZNF197
ZNF365
ZNF76
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Entrez ID |
8658 |
27185 |
HPRD ID |
04490 |
05553 |
Ensembl ID |
ENSG00000173273
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ENSG00000162946
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Uniprot IDs |
O95271
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C4P094
C4P096
C4P098
C4P0A4
C4P0A5
C4P0C4
C4P0C8
C4P0D0
C4P0D1
C4P0D2
C4P0D3
Q9NRI5
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PDB IDs |
2RF5
3UDD
3UH2
3UH4
4DVI
4I9I
4K4E
4K4F
4KRS
4LI6
4LI7
4LI8
4MSG
4MSK
4MT9
4N3R
4N4V
4OA7
4TOR
4TOS
4U6A
4UUH
4UW1
4W5S
4W6E
5EBT
5ECE
5ETY
5GP7
5JHQ
5JTI
5JU5
5KNI
6QXU
6URQ
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5V4B
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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