TNKS and USP25

TNKS

USP25

Description tankyrase ubiquitin specific peptidase 25
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Bipolar disorder ( 31043756)
  • Bone mineral density (Ward's triangle area) ( 27397699)
  • Brain morphology (MOSTest) ( 32665545)
  • Cataracts (operation) ( 31816047)
  • Deep white matter hyperintensities ( 32517579)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Fish- and plant-related diet ( 32066663)
  • General risk tolerance (MTAG) ( 30643258)
  • Joint mobility (Beighton score) ( 27182965)
  • LDL cholesterol levels ( 32203549)
  • Metabolite levels ( 22916037)
  • Mosquito bite size ( 28199695)
  • Nose size ( 27182965)
  • Obesity (early onset extreme) ( 20421936)
  • Oily fish consumption ( 32066663)
  • Pork consumption ( 32066663)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Refractive error ( 32231278)
  • Regular attendance at a religious group ( 29970889)
  • Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
  • Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578)
  • Schizophrenia ( 26198764)
  • Systemic lupus erythematosus ( 28714469)
  • Systolic blood pressure ( 30224653)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Triglyceride levels ( 32154731)
  • Type 2 diabetes ( 30054458)
Interacting Genes 25 interacting genes: ADPRS ANKRD28 BABAM1 DISC1 EIF4A1 EPM2AIP1 FANCD2 FNBP1 LNPEP MCL1 NELFE NUMA1 OARD1 POT1 PTEN SDCBP SH3BP5 TCL1A TERF1 TNIK TNKS1BP1 TNKS2 UBASH3B USP25 VPS33A 21 interacting genes: ACTA1 FBXL17 FLNC GAPDH MAGEB4 MID2 MT2A PUS10 RAD23A RAD23B SENP1 SKIL SUMO1 SUMO2 SUMO3 SYK TMEM43 TNKS UBC UBE2I ZNF426
Entrez ID 8658 29761
HPRD ID 04490 05296
Ensembl ID ENSG00000173273 ENSG00000155313
Uniprot IDs O95271 Q9UHP3
PDB IDs 2RF5 3UDD 3UH2 3UH4 4DVI 4I9I 4K4E 4K4F 4KRS 4LI6 4LI7 4LI8 4MSG 4MSK 4MT9 4N3R 4N4V 4OA7 4TOR 4TOS 4U6A 4UUH 4UW1 4W5S 4W6E 5EBT 5ECE 5ETY 5GP7 5JHQ 5JTI 5JU5 5KNI 6QXU 6URQ 2MUX 5GP7 5O71 6H4J 6H4K 6HEL 6HEM
Enriched GO Terms of Interacting Partners?
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