Description |
DISC1 scaffold protein |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Alzheimer's disease ( 19118814)
- Amyotrophic lateral sclerosis ( 19451621)
- Amyotrophic lateral sclerosis (sporadic) ( 24529757)
- Arterial stiffness index ( 31235810)
- Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451)
- Metabolite levels ( 23823483)
- Neuranatomic and neurocognitive phenotypes ( 21483430)
- Pelvic organ prolapse (moderate/severe) ( 26545240)
- Response to antidepressants (symptom improvement) ( 29160301)
- Response to antineoplastic agents ( 21659360)
- Response to statin therapy ( 20339536)
- Serum docosahexaenoic fatty acid concentration in metabolic syndrome ( 31991592)
- Waist circumference ( 28552196)
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- Body fat distribution (arm fat ratio) ( 30664634)
- Body fat distribution (leg fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
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Interacting Genes |
188 interacting genes:
ABI2
ACTG1
ACTN2
ADO
AGTPBP1
AIMP2
AKAP6
AMOT
AP1M1
ARIH2
ARMC7
ATF4
ATF5
ATF7IP
BAG2
BFSP2
BICD1
BORCS6
BRD1
C1orf109
C2CD6
C8orf33
CARD9
CCDC102B
CCDC13
CCDC136
CCDC141
CCDC197
CCDC24
CCDC57
CCDC88A
CCDC92
CCHCR1
CDC23
CDC37
CDC5L
CDK5RAP3
CDKL3
CEP126
CEP57
CEP57L1
CEP63
CFAP206
CIT
CLU
COL4A1
CTNNA3
CWF19L2
DCTN1
DCTN2
DDX6
DMD
DNAJC7
DPYSL2
DPYSL3
DST
DYNC1H1
EEF2
EIF3H
EIF4A3
EMSY
EXOC1
EXOC4
EXOC7
FBXO34
FBXO41
FBXW7
FEZ1
FLACC1
FRYL
GABARAPL1
GAS2L2
GAS8
GCC1
GEM
GNB1
GNG13
GNPTAB
GPANK1
GPRASP2
GRIPAP1
GSK3B
HERC2P2
HNRNPC
IFT20
IFT74
IMMT
ITSN1
KALRN
KANSL1
KCNQ5
KIF3A
KIF3C
KIF9
KIFAP3
KIFC3
LENG1
MACF1
MAP1A
MEMO1
MLLT10
MNS1
MORF4L2
MPPED1
MVP
MYH7
MYT1L
NCK2
NDE1
NDEL1
NECAB1
NEFM
NME7
NSRP1
NUP160
OLFM1
PCNT
PCNX4
PDE4B
PGK1
PHF1
PIBF1
PIK3R3
PKN1
POLR3C
PPFIA3
PPM1E
PPP4R1
PPP5C
PSPC1
QARS1
RABGAP1
RAD21
RANBP9
RASSF7
RBM41
RBSN
RECK
RNF40
ROGDI
RTRAF
SH3BP5
SMARCD1
SMARCE1
SMC2
SMC3
SMC5
SMYD1
SNX6
SPARCL1
SPATC1L
SPTBN4
SRGAP2
SRGAP3
STX11
STX18
SUFU
SYBU
SYNE1
TCAF1
TCEANC
TFIP11
TIAM2
TNKS
TRAF3IP1
TRAF4
TRIM29
TRIM68
TRIO
TSGA10
TSPOAP1
TSR2
TTC23
TUBB
TUBB2A
UBASH3A
UBASH3B
USP2
UTRN
XPNPEP1
YWHAE
YWHAG
YWHAQ
YWHAZ
ZNF124
ZNF197
ZNF365
ZNF76
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156 interacting genes:
ABI1
ABI2
ABI3
ADAT2
ANKRD23
ANKRD49
ANKS1A
ANP32B
APOA5
AR
ARMC10
ARRDC3
BCAS2
BEND5
BEX3
BHLHB9
BLOC1S5
BRWD1
C19orf54
C1orf109
C4BPA
CALCOCO2
CCDC102B
CCDC130
CCDC197
CCDC33
CCDC85B
CDC5L
CDR2
CDSN
CDX2
CEACAM6
CHFR
CHN2
CLNK
COG6
COL1A2
CORO1A
CUEDC1
CYSRT1
DCTN2
DISC1
EGFL7
EIF4G1
ESR1
ESS2
FAM136A
FAM161A
FBXO7
FEZ1
FOS
FUS
GATA1
GCC1
GIGYF1
GINS3
GOLGA6L9
GRAMD4
HES6
HNRNPC
HOMEZ
HOXD3
HSF2BP
HSPB1
IGKC
IKBIP
IKZF3
INSC
IQCB1
JUN
KATNBL1
KDM1A
KEAP1
KIAA0753
KLF1
KMT5B
KRT15
KRT16
KRT18
KRT27
KRT31
KRT34
KRT37
KRT38
KRT75
LDB2
LDOC1
LZTS2
MAGEA2
MAGEA2B
MAGEA6
MED4
MKRN3
MTNR1B
MTUS2
NAB2
NECAB2
NELFA
NME1
NONO
NR1H4
NR3C1
NUCB2
NUDT16L1
NUTM1
PACSIN3
PAICS
PBX4
PCBD1
PGR
PICK1
PIH1D1
PKNOX2
PLAGL2
PPM1J
PRDX1
PRMT6
PSTPIP1
RIF1
RORB
RPS29
SCARA5
SCHIP1
SCNM1
SERTAD3
SHISA6
SMARCB1
SMUG1
SNF8
SPSB2
STH
STMN3
SYCE1L
TCP10L
THOC7
TLE5
TNIP2
TP53
TRIM27
TRIM54
TRIM72
USHBP1
USP54
VPS37B
WASHC1
WWP2
YWHAG
ZC2HC1C
ZMAT5
ZMYND12
ZNF417
ZNF438
ZNF511
ZNF629
ZNF655
ZNF69
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Entrez ID |
27185 |
6602 |
HPRD ID |
05553 |
03438 |
Ensembl ID |
ENSG00000162946
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ENSG00000066117
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Uniprot IDs |
C4P094
C4P096
C4P098
C4P0A4
C4P0A5
C4P0C4
C4P0C8
C4P0D0
C4P0D1
C4P0D2
C4P0D3
Q9NRI5
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Q96GM5
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PDB IDs |
5V4B
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6LTH
6LTJ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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