THOC5 and PPIL1

Data Source:
BioGRID (two hybrid, two hybrid)

		THOC5	PPIL1
Description		THO complex 5	peptidylprolyl isomerase like 1
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	MRNA Binding Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Disordered Domain Specific Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing Monocyte Differentiation MRNA 3'-end Processing Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Primitive Hemopoiesis Negative Regulation Of DNA Damage Checkpoint	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Carotid atherosclerosis in HIV infection ( 20009918) HDL cholesterol levels ( 32203549) Lipid traits ( 24023261)	Acne (severe) ( 24927181) Blood protein levels ( 30072576 29875488) Heart rate ( 28610988) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Resting heart rate ( 27798624) Weight ( 28552196)
Interacting Genes		11 interacting genes: CSF1R CSNK2A1 HSPB1 LIG4 LSM3 NXF1 OXTR PPIL1 PRKCA THOC7 ZNF830	24 interacting genes: COL17A1 CPSF6 DDIT4L GADD45G HNRNPA1 HNRNPUL1 KPRP LHX2 LNX2 N4BP2L2 POU6F2 PPP1R8 PRR22 PRR35 RBM42 RIMBP3 SF3B3 SNW1 SPDYE4 SRPK1 SRPK2 TCF4 THOC5 WDR77
Entrez ID		8563	51645
HPRD ID		16650	03194
Ensembl ID		ENSG00000100296	ENSG00000137168
Uniprot IDs		A0A024R1D6 Q13769	A0A024RCX8 Q9Y3C6
PDB IDs			1XWN 2K7N 2X7K 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM
Enriched GO Terms of Interacting Partners?
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