PPIL1 and SPDYE4

Data Source:
BioGRID (two hybrid)

		PPIL1	SPDYE4
Description		peptidylprolyl isomerase like 1	speedy/RINGO cell cycle regulator family member E4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Disordered Domain Specific Binding	Protein Binding Protein Kinase Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576 29875488) Heart rate ( 28610988) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Resting heart rate ( 27798624) Weight ( 28552196)	Attention deficit hyperactivity disorder ( 29325848)
Interacting Genes		24 interacting genes: COL17A1 CPSF6 DDIT4L GADD45G HNRNPA1 HNRNPUL1 KPRP LHX2 LNX2 N4BP2L2 POU6F2 PPP1R8 PRR22 PRR35 RBM42 RIMBP3 SF3B3 SNW1 SPDYE4 SRPK1 SRPK2 TCF4 THOC5 WDR77	11 interacting genes: CDK3 CDK5 CKS1B GCK GPKOW MAGOHB NTAQ1 PPIL1 QARS1 TBC1D13 USP2
Entrez ID		51645	388333
HPRD ID		03194
Ensembl ID		ENSG00000137168	ENSG00000183318
Uniprot IDs		A0A024RCX8 Q9Y3C6	A6NLX3
PDB IDs		1XWN 2K7N 2X7K 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM
Enriched GO Terms of Interacting Partners?
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