DENR and NELFB

Data Source:
BioGRID (pull down)

		DENR	NELFB
Description		density regulated re-initiation and release factor	negative elongation factor complex member B
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GO Annotations	Cellular Component	Cellular_component	Nucleoplasm Cytoplasm NELF Complex
	Molecular Function	Molecular_function MRNA Binding Translation Initiation Factor Activity Protein Binding	RNA Binding Protein Binding
	Biological Process	Formation Of Translation Preinitiation Complex Translation Reinitiation Ribosome Disassembly IRES-dependent Viral Translational Initiation	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Cell Population Proliferation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Stem Cell Differentiation Positive Regulation Of Viral Transcription Negative Regulation Of Stem Cell Differentiation
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation NTRK3 as a dependence receptor
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355)
Interacting Genes		3 interacting genes: MCTS1 NELFB UBC	16 interacting genes: BRCA1 CEBPE DENR ESR1 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFA NELFCD NELFE NTRK3 RAD51 TPRX1
Entrez ID		8562	25920
HPRD ID		05182	10845
Ensembl ID		ENSG00000139726	ENSG00000188986
Uniprot IDs		A0A024RBR3 O43583	Q8WX92
PDB IDs		5ONS 5VYC 6MS4 6VPQ 6VPR	6GML
Enriched GO Terms of Interacting Partners?
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