NELFB and DENR

Data Source:
BioGRID (pull down)

		NELFB	DENR
Description		negative elongation factor complex member B	density regulated re-initiation and release factor
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm NELF Complex	Cellular_component
	Molecular Function	RNA Binding Protein Binding	Molecular_function MRNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Cell Population Proliferation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Stem Cell Differentiation Positive Regulation Of Viral Transcription Negative Regulation Of Stem Cell Differentiation	Formation Of Translation Preinitiation Complex Translation Reinitiation Ribosome Disassembly IRES-dependent Viral Translational Initiation
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation NTRK3 as a dependence receptor
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355)
Interacting Genes		16 interacting genes: BRCA1 CEBPE DENR ESR1 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFA NELFCD NELFE NTRK3 RAD51 TPRX1	3 interacting genes: MCTS1 NELFB UBC
Entrez ID		25920	8562
HPRD ID		10845	05182
Ensembl ID		ENSG00000188986	ENSG00000139726
Uniprot IDs		Q8WX92	A0A024RBR3 O43583
PDB IDs		6GML	5ONS 5VYC 6MS4 6VPQ 6VPR
Enriched GO Terms of Interacting Partners?
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