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NELFB and NELFE
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
NELFB
NELFE
Description
negative elongation factor complex member B
negative elongation factor complex member E
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
NELF Complex
Nucleus
Nucleoplasm
Plasma Membrane
Nuclear Body
NELF Complex
Molecular Function
RNA Binding
Protein Binding
Chromatin Binding
RNA Binding
Protein Binding
Biological Process
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Cell Population Proliferation
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Stem Cell Differentiation
Positive Regulation Of Viral Transcription
Negative Regulation Of Stem Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Positive Regulation Of Histone H3-K4 Methylation
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of MRNA Polyadenylation
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
NTRK3 as a dependence receptor
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Asthma (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Coronary artery disease (
29212778
)
Disease progression in age-related macular degeneration (
29346644
)
Inflammatory bowel disease (
28067908
)
Ulcerative colitis (
28067908
)
vWF levels (
30586737
)
Interacting Genes
16 interacting genes:
BRCA1
CEBPE
DENR
ESR1
FOS
HSPA9
JUN
KHDRBS3
MAPK6
MGST1
NELFA
NELFCD
NELFE
NTRK3
RAD51
TPRX1
10 interacting genes:
CACTIN
CCDC57
MTUS2
NCOR1
NELFB
SRPK1
SRPK2
TNKS
TRIM27
VAMP3
Entrez ID
25920
7936
HPRD ID
10845
01096
Ensembl ID
ENSG00000188986
ENSG00000204356
Uniprot IDs
Q8WX92
A0A1U9X830
P18615
PDB IDs
6GML
1X5P
2BZ2
2JX2
5OOB
6GML
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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