MICALL1 and ZP3

Data Source:
BioGRID (two hybrid)

		MICALL1	ZP3
Description		MICAL like 1	zona pellucida glycoprotein 3
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Late Endosome Trans-Golgi Network Extrinsic Component Of Membrane Late Endosome Membrane Recycling Endosome Membrane	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix Egg Coat Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Metal Ion Binding Phosphatidic Acid Binding	Extracellular Matrix Structural Constituent Protein Binding Carbohydrate Binding Acrosin Binding Structural Constituent Of Egg Coat Identical Protein Binding Receptor Ligand Activity
	Biological Process	Protein Targeting To Membrane Endocytosis Receptor-mediated Endocytosis Neuron Projection Development Slow Endocytic Recycling Protein Localization To Endosome Plasma Membrane Tubulation Retrograde Transport, Endosome To Plasma Membrane	Positive Regulation Of Type IV Hypersensitivity Blastocyst Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Leukocyte Migration Positive Regulation Of Humoral Immune Response Binding Of Sperm To Zona Pellucida Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-4 Production Egg Coat Formation Positive Regulation Of T Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Phosphatidylinositol-mediated Signaling Oocyte Development Positive Regulation Of Inflammatory Response Positive Regulation Of Acrosome Reaction Negative Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Antral Ovarian Follicle Growth
Pathways			Interaction With Cumulus Cells And The Zona Pellucida
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252)	Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		8 interacting genes: EHD1 EHD3 RAB13 RAB1A RFFL YWHAB YWHAG ZP3	11 interacting genes: ACR CLDN11 ENGASE FURIN MALL MICALL1 MRPS16 OR2L13 PCDH17 SPACA3 UBAP2L
Entrez ID		85377	7784
HPRD ID		11363	01690
Ensembl ID		ENSG00000100139	ENSG00000188372
Uniprot IDs		Q8N3F8	P21754
PDB IDs		2KSP
Enriched GO Terms of Interacting Partners?
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