ZP3 and MRPS16

Data Source:
BioGRID (two hybrid)

		ZP3	MRPS16
Description		zona pellucida glycoprotein 3	mitochondrial ribosomal protein S16
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix Egg Coat Collagen-containing Extracellular Matrix	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Cytosol Small Ribosomal Subunit
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Carbohydrate Binding Acrosin Binding Structural Constituent Of Egg Coat Identical Protein Binding Receptor Ligand Activity	Structural Constituent Of Ribosome Protein Binding
	Biological Process	Positive Regulation Of Type IV Hypersensitivity Blastocyst Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Leukocyte Migration Positive Regulation Of Humoral Immune Response Binding Of Sperm To Zona Pellucida Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-4 Production Egg Coat Formation Positive Regulation Of T Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Phosphatidylinositol-mediated Signaling Oocyte Development Positive Regulation Of Inflammatory Response Positive Regulation Of Acrosome Reaction Negative Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Antral Ovarian Follicle Growth	Translation Mitochondrial Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Interaction With Cumulus Cells And The Zona Pellucida	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases			Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		11 interacting genes: ACR CLDN11 ENGASE FURIN MALL MICALL1 MRPS16 OR2L13 PCDH17 SPACA3 UBAP2L	2 interacting genes: ATXN10 ZP3
Entrez ID		7784	51021
HPRD ID		01690	14778
Ensembl ID		ENSG00000188372	ENSG00000182180
Uniprot IDs		P21754	Q9Y3D3
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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