ZP3 and MICALL1

Data Source:
BioGRID (two hybrid)

		ZP3	MICALL1
Description		zona pellucida glycoprotein 3	MICAL like 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix Egg Coat Collagen-containing Extracellular Matrix	Early Endosome Late Endosome Trans-Golgi Network Extrinsic Component Of Membrane Late Endosome Membrane Recycling Endosome Membrane
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Carbohydrate Binding Acrosin Binding Structural Constituent Of Egg Coat Identical Protein Binding Receptor Ligand Activity	Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Metal Ion Binding Phosphatidic Acid Binding
	Biological Process	Positive Regulation Of Type IV Hypersensitivity Blastocyst Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Leukocyte Migration Positive Regulation Of Humoral Immune Response Binding Of Sperm To Zona Pellucida Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-4 Production Egg Coat Formation Positive Regulation Of T Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Phosphatidylinositol-mediated Signaling Oocyte Development Positive Regulation Of Inflammatory Response Positive Regulation Of Acrosome Reaction Negative Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Antral Ovarian Follicle Growth	Protein Targeting To Membrane Endocytosis Receptor-mediated Endocytosis Neuron Projection Development Slow Endocytic Recycling Protein Localization To Endosome Plasma Membrane Tubulation Retrograde Transport, Endosome To Plasma Membrane
Pathways		Interaction With Cumulus Cells And The Zona Pellucida
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)	Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252)
Interacting Genes		11 interacting genes: ACR CLDN11 ENGASE FURIN MALL MICALL1 MRPS16 OR2L13 PCDH17 SPACA3 UBAP2L	8 interacting genes: EHD1 EHD3 RAB13 RAB1A RFFL YWHAB YWHAG ZP3
Entrez ID		7784	85377
HPRD ID		01690	11363
Ensembl ID		ENSG00000188372	ENSG00000100139
Uniprot IDs		P21754	Q8N3F8
PDB IDs			2KSP
Enriched GO Terms of Interacting Partners?
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