Description |
CRK proto-oncogene, adaptor protein |
Cbl proto-oncogene C |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
- Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
- Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
- Apolipoprotein B levels ( 32203549)
- Body mass index ( 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x age interaction ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
- LDL cholesterol ( 24507774)
- Weight ( 28552196)
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Interacting Genes |
169 interacting genes:
ABL1
ABL2
ANKZF1
ANLN
AR
ARHGAP17
ARHGAP32
ASAP1
ASAP3
ASCL4
ATF3
ATXN1
AVIL
BATF3
BCAR1
BCR
BEX5
BUB1
C1orf94
C4orf17
C6orf141
CBL
CBLB
CBLC
CHTF18
CLNK
CNDP2
CORO6
CRKL
DAB1
DOCK1
DOCK3
DOK1
DOK2
DOK3
DOK4
DOK7
DPPA4
EFS
EGFR
ELK1
ELK3
EPHA3
EPHB2
EPHB3
EPHB6
EPS15
EPYC
ERBB2
ERBB3
ERBB4
ESD
EYA3
FASLG
FER
FGFR1
FLACC1
FLT1
FRS2
FSTL1
FYN
GAB1
GABPB2
GAREM1
GRB2
HABP4
HSH2D
IFT140
IGF1R
IKZF3
INO80E
INSR
IRS1
IRS2
IRS4
ISL1
KCTD13
KCTD17
KDR
KHDRBS1
KIT
KLF15
KLHL20
LASP1
LHX8
LNX2
MAGEC3
MAP4K1
MAP4K5
MAPK4
MAPK8
MET
MICAL1
MNDA
MPG
MYLIP
MYOZ2
NCK1
NEDD9
NTRK1
NUFIP2
OFCC1
PAFAH1B2
PDGFRA
PDGFRB
PHC2
PIK3R1
PIK3R2
PIK3R3
PLSCR1
POT1
PPFIBP2
PPP1CA
PRKACA
PRRC2B
PRRG2
PSMC1
PSMC6
PTK2
PTK2B
PTPN1
PTPN4
PTPRH
PTTG1
PXN
RAB2B
RAPGEF1
REPS1
RET
RIN3
RTCB
RYBP
SASH1
SAXO1
SEMA4D
SEPTIN6
SETD9
SH2D2A
SH3BP1
SHB
SHC1
SOCS1
SOCS6
SOS1
SPRR2A
STAT4
STAT5A
STAT5B
STRN4
SYN1
TCAP
TDG
TERF2IP
TM4SF19
TP53
TP53BP2
TUBA1C
TWIST2
TXK
USP53
VAC14
VAV1
WASF1
WDR83
WEE1
XPO1
ZAP70
ZKSCAN7
ZNF557
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54 interacting genes:
AKT1
BAP1
BIRC2
CCND2
CDK6
CDKN2B
CHFR
CKM
CRK
EGFR
EPHA2
ERBB2
FGFR4
FYN
GLIS2
GRB2
ITCH
LATS2
LYN
MAP2K3
MDM4
MYC
NACAD
NF2
NFIC
NSD3
OTUD6A
OXA1L
RAF1
SH3GL3
SHC1
SPRY2
SRC
STK11
TERT
TGFB1I1
TP53
TRAF4
TRIM46
TRIP6
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2H
UBE2I
UBE2K
UBE2L3
UBE2L6
UBE2R2
USP2
USP21
YES1
ZAP70
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Entrez ID |
1398 |
23624 |
HPRD ID |
01267 |
09765 |
Ensembl ID |
ENSG00000167193
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ENSG00000142273
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Uniprot IDs |
A0A0S2Z3K9
A0A0S2Z3Q4
L7RT18
P46108
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Q9ULV8
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PDB IDs |
1JU5
2DVJ
2EYV
2EYW
2EYX
2EYY
2EYZ
2MS4
5UL6
6ATV
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3OP0
3VRN
3VRO
3VRP
3VRQ
3VRR
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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