PPFIA2 and IPO13

Data Source:
BioGRID (affinity chromatography technology)

		PPFIA2	IPO13
Description		PTPRF interacting protein alpha 2	importin 13
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cell Surface Axon Dendritic Spine Presynaptic Active Zone Extracellular Exosome Glutamatergic Synapse	Nucleus Cytoplasm
	Molecular Function	Protein Binding Structural Constituent Of Presynapse	Protein Binding
	Biological Process	Cell-matrix Adhesion Neurotransmitter Secretion Glutamate Secretion Synapse Organization Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Presynapse Organization Dense Core Granule Cytoskeletal Transport Regulation Of Synaptic Vesicle Exocytosis	Protein Import Into Nucleus
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Age-related cataracts (age at onset) ( 25352737) Alcohol dependence ( 26365420) Delirium ( 29631748) Lean body mass ( 28552196) Post bronchodilator FEV1 ( 26634245) Resting heart rate ( 27798624) Schizophrenia ( 22885689)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		13 interacting genes: CAST CDC5L ERC2 GIT1 ITSN1 MTDH PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS	17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I
Entrez ID		8499	9670
HPRD ID		04392	13742
Ensembl ID		ENSG00000139220	ENSG00000117408
Uniprot IDs		B7Z7Y5 G3V200 H0YHK3 O75334 Q4LE62	O94829
PDB IDs		3TAC 3TAD 6IUH	2X19 2XWU 3ZJY
Enriched GO Terms of Interacting Partners?
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