IGSF21 and NREP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IGSF21	NREP
Description		immunoglobin superfamily member 21	neuronal regeneration related protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse	Nucleus Cytoplasm
	Molecular Function		Protein Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation	Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Axon Regeneration Regulation Of Neuron Differentiation
Pathways
Drugs
Diseases
GWAS		Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)	Apolipoprotein A1 levels ( 32203549) Breast cancer ( 29059683) Gut microbiota relative abundance (Sutterella) ( 33208821) Hematocrit ( 32888494) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reaction time ( 29844566) Red blood cell count ( 29403010 32888494) Thyroid cancer ( 28195142)
Interacting Genes		32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2	5 interacting genes: ATM EEF1A1 EIF3B IGSF21 KMT2B
Entrez ID		84966	9315
HPRD ID		11309	09545
Ensembl ID		ENSG00000117154	ENSG00000134986
Uniprot IDs		Q96ID5	Q16612
PDB IDs
Enriched GO Terms of Interacting Partners?
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