IGSF21 and ETHE1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IGSF21	ETHE1
Description		immunoglobin superfamily member 21	ETHE1 persulfide dioxygenase
Image		No pdb structure
GO Annotations	Cellular Component	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function		Iron Ion Binding Protein Binding Hydrolase Activity, Acting On Ester Bonds Identical Protein Binding Sulfur Dioxygenase Activity
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation	Glutathione Metabolic Process Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase Hydrogen Sulfide Metabolic Process
Pathways			Sulfide oxidation to sulfate
Drugs
Diseases
GWAS		Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)
Interacting Genes		32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2	9 interacting genes: APP ATG9A ATP6V1H GORASP2 IGSF21 KRTAP19-2 LRIF1 RELA TXN2
Entrez ID		84966	23474
HPRD ID		11309	09764
Ensembl ID		ENSG00000117154	ENSG00000105755
Uniprot IDs		Q96ID5	A0A0S2Z580 A0A0S2Z5B3 A0A0S2Z5N8 B2RCZ7 O95571
PDB IDs			4CHL
Enriched GO Terms of Interacting Partners?
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