ZNF503 and PROP1

Data Source:
BioGRID (two hybrid)

		ZNF503	PROP1
Description		zinc finger protein 503	PROP paired-like homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Binding Metal Ion Binding Repressing Transcription Factor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Neural Precursor Cell Proliferation G1 To G0 Transition Involved In Cell Differentiation	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Pituitary Gland Development
Pathways
Drugs
Diseases			Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS		Metabolite levels ( 23823483) Triglyceride levels ( 32203549) Type 2 diabetes ( 30718926)
Interacting Genes		10 interacting genes: ARID5A ATN1 DTX2 FOXH1 KRTAP19-1 KRTAP3-3 KRTAP6-2 PROP1 TENT5B TLE5	54 interacting genes: ABHD11 ARSA BATF2 C11orf1 C19orf54 C1orf94 C6orf15 C9orf24 COX6B2 CRYBA1 CYSRT1 DAZAP2 EFEMP2 FAM166A FAM168A HDHD3 HESX1 HNRNPF HOXA1 INTS11 KHDC1 KRTAP13-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP6-3 KRTAP8-1 MAGED1 METTL15 METTL27 NR1D2 OLIG3 OXER1 P4HA3 PITX2 PLEKHB2 POU6F2 PSMB11 PSMB4 RNF144B RNF4 SMUG1 SUMO1 TBX22 TEKT4 TEKT5 TENT5B TINAGL1 TLE5 TMEM42 TRIM42 UBE2I UFSP1 ZNF503
Entrez ID		84858	5626
HPRD ID		15811	03325
Ensembl ID		ENSG00000165655	ENSG00000175325
Uniprot IDs		Q96F45	A0A0G2JQ02 O75360
PDB IDs
Enriched GO Terms of Interacting Partners?
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