TXNDC17 and RUFY1

Data Source:
BioGRID (two hybrid)

		TXNDC17	RUFY1
Description		thioredoxin domain containing 17	RUN and FYVE domain containing 1
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Peroxidase Activity Protein Binding Protein-disulfide Reductase Activity	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Tumor Necrosis Factor-mediated Signaling Pathway Cellular Oxidant Detoxification	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		9 interacting genes: AVP DYNLL1 EXOSC8 INCA1 INS OXT RUFY1 TINF2 TXNRD1	18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25
Entrez ID		84817	80230
HPRD ID		11656	15282
Ensembl ID		ENSG00000129235	ENSG00000176783
Uniprot IDs		A0A140VJY7 Q9BRA2	A8K7B1 Q96T51
PDB IDs		1WOU	2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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