RUFY1 and AP3S1

Data Source:
BioGRID (pull down)

		RUFY1	AP3S1
Description		RUN and FYVE domain containing 1	adaptor related protein complex 3 subunit sigma 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle	Golgi Apparatus AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Axon Cytoplasm
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding	Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis	Intracellular Protein Transport Anterograde Axonal Transport Insulin Receptor Signaling Pathway Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		Synthesis of PIPs at the plasma membrane	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25	7 interacting genes: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3
Entrez ID		80230	1176
HPRD ID		15282	03298
Ensembl ID		ENSG00000176783	ENSG00000177879
Uniprot IDs		A8K7B1 Q96T51	F5H459 Q92572
PDB IDs		2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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