TXNDC17 and OXT

Data Source:
HPRD (in vitro)

		TXNDC17	OXT
Description		thioredoxin domain containing 17	oxytocin/neurophysin I prepropeptide
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Extracellular Region Extracellular Space Secretory Granule Terminal Bouton
	Molecular Function	Peroxidase Activity Protein Binding Protein-disulfide Reductase Activity	Neuropeptide Hormone Activity Neurohypophyseal Hormone Activity Protein Binding Oxytocin Receptor Binding
	Biological Process	Tumor Necrosis Factor-mediated Signaling Pathway Cellular Oxidant Detoxification	Response To Amphetamine Regulation Of Heart Rate Maternal Aggressive Behavior Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Heart Development Female Pregnancy Memory Grooming Behavior Response To Sucrose Positive Regulation Of Norepinephrine Secretion Response To Activity Sleep Response To Food Positive Regulation Of Prostaglandin Secretion Response To Estradiol Response To Retinoic Acid Response To Progesterone Response To Prostaglandin E Social Behavior Negative Regulation Of Urine Volume Positive Regulation Of Renal Sodium Excretion Response To Cocaine Hyperosmotic Salinity Response Maternal Behavior Sperm Ejaculation Eating Behavior Drinking Behavior Response To Peptide Hormone Response To Ether Negative Regulation Of Blood Pressure Positive Regulation Of Blood Pressure Positive Regulation Of Ossification Positive Regulation Of Female Receptivity Positive Regulation Of Synaptic Transmission Response To Glucocorticoid Response To CAMP Response To Electrical Stimulus Regulation Of Sensory Perception Of Pain Positive Regulation Of Synapse Assembly Male Mating Behavior Positive Regulation Of Penile Erection Positive Regulation Of Hindgut Contraction Negative Regulation Of Gastric Acid Secretion Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Cold-induced Thermogenesis
Pathways			Vasopressin-like receptors G alpha (q) signalling events
Drugs			Oxytocin
Diseases
GWAS		LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Blood protein levels ( 30072576) Serum oxytocin levels ( 31361301)
Interacting Genes		9 interacting genes: AVP DYNLL1 EXOSC8 INCA1 INS OXT RUFY1 TINF2 TXNRD1	5 interacting genes: ESR2 KMT2A OXTR PREP TXNDC17
Entrez ID		84817	5020
HPRD ID		11656	08880
Ensembl ID		ENSG00000129235	ENSG00000101405
Uniprot IDs		A0A140VJY7 Q9BRA2	P01178 X5D7M6
PDB IDs		1WOU
Enriched GO Terms of Interacting Partners?
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