SPSB2 and DDX4

Data Source:
BioGRID (unspecified method)

		SPSB2	DDX4
Description		splA/ryanodine receptor domain and SOCS box containing 2	DEAD-box helicase 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol SCF Ubiquitin Ligase Complex	Nucleus Cytoplasm P Granule Perinuclear Region Of Cytoplasm Pi-body PiP-body
	Molecular Function	Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	RNA Binding RNA Helicase Activity ATP Binding ATPase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Viral Process Protein Ubiquitination Intracellular Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Male Meiotic Nuclear Division Male Meiosis I Multicellular Organism Development Gamete Generation Spermatogenesis Negative Regulation Of Transposition Cell Differentiation Flagellated Sperm Motility Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation PiRNA Biosynthetic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS		Colorectal cancer ( 26965516) Refractive error ( 32231278)	Cocaine dependence ( 31212010)
Interacting Genes		12 interacting genes: APP DDX4 FNDC3B GALNT15 NOS2 NRF1 PAWR PRMT1 RECK SMARCD1 TRIM55 TRIM63	5 interacting genes: PIWIL2 RANBP9 SPSB1 SPSB2 SPSB4
Entrez ID		84727	54514
HPRD ID		13610	05593
Ensembl ID		ENSG00000111671	ENSG00000152670
Uniprot IDs		Q99619	Q9NQI0
PDB IDs		3EMW 5XN3 6DN5 6DN6 6JKJ 6JWM 6JWN 6KEY
Enriched GO Terms of Interacting Partners?
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