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TUBA4A and RAB8B
Data Source:
HPRD
(in vivo)
TUBA4A
RAB8B
Description
tubulin alpha 4a
RAB8B, member RAS oncogene family
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Cytoplasm
Cytosol
Cytoskeleton
Microtubule
Microtubule Cytoskeleton
Extracellular Exosome
Nucleoplasm
Endosome
Peroxisomal Membrane
Plasma Membrane
Synaptic Vesicle
Nuclear Body
Trans-Golgi Network Transport Vesicle
Phagocytic Vesicle Membrane
Intracellular Membrane-bounded Organelle
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Cell Tip
Recycling Endosome Membrane
Extracellular Exosome
Molecular Function
GTPase Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Protein Kinase Binding
GTPase Activity
Signaling Receptor Binding
Protein Binding
GTP Binding
GDP Binding
TPR Domain Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Platelet Degranulation
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Ciliary Basal Body-plasma Membrane Docking
Vesicle Docking Involved In Exocytosis
Protein Secretion
Regulation Of Exocytosis
Antigen Processing And Presentation
Positive Regulation Of Cell Projection Organization
Cellular Response To Insulin Stimulus
Protein Import Into Peroxisome Membrane
Golgi Vesicle Fusion To Target Membrane
Positive Regulation Of Corticotropin Secretion
Cilium Assembly
Protein Localization To Plasma Membrane
Cell-substrate Junction Organization
Pathways
Platelet degranulation
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Cilium Assembly
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
TBC/RABGAPs
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Drugs
Vincristine
Podofilox
Epothilone D
Patupilone
CYT997
Cabazitaxel
Phenethyl Isothiocyanate
Phosphoaminophosphonic acid guanylate ester
Guanosine-5'-Diphosphate
Diseases
GWAS
Platelet distribution width (
32888494
27863252
)
Refractive error (
32231278
)
Serum metabolite levels (
23093944
)
Social communication problems (
24564958
)
Interacting Genes
51 interacting genes:
APC
ARHGAP1
B4GALT1
BCAR1
BRCA1
C4orf17
CALB2
EGFR
ENO2
EPB41
FYN
GNAI2
GPHN
GRM7
HDAC6
HSPH1
LGALS2
LTA
MAGED1
MAP1A
MAP1LC3A
MAPT
MARK4
MYC
NCALD
PFDN4
PLK1
PRKN
RAB8B
RAC1
RACGAP1
RBM23
RTN4
S100A8
SIAH1
SIMC1
SIRT2
STARD13
SUMO2
SYK
TAOK2
TBCB
TBCE
TCP1
TCP11L2
TM4SF1
UCHL5
VAV1
VDAC1
YWHAG
ZAP70
7 interacting genes:
APP
CDH1
RAB3IP
RALA
TUBA4A
TUBB
VIM
Entrez ID
7277
51762
HPRD ID
01851
11476
Ensembl ID
ENSG00000127824
ENSG00000166128
Uniprot IDs
P68366
Q92930
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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