DYRK2 and EIF2B5

  • Data Source:
  • BioGRID (enzymatic study)



Description dual specificity tyrosine phosphorylation regulated kinase 2 eukaryotic translation initiation factor 2B subunit epsilon
GO Annotations Cellular Component
Molecular Function
Biological Process
  • Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728)
  • Daytime sleep phenotypes ( 27126917)
  • Itch intensity from mosquito bite ( 28199695)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Malaria ( 31844061)
  • Metabolite levels ( 23823483)
  • Mosquito bite size ( 28199695)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 22 interacting genes: APP ATM DYRK4 EIF2B5 H2BC21 H3-4 IKZF1 KATNA1 KXD1 LRRK2 LZTS2 MAPT MDM2 NR1I2 RAD54B SIAH2 SP100 TERT UBE2D1 UBR5 WDR62 ZBTB9 12 interacting genes: APP CHMP2A CSNK1A1 CSNK2A1 CSNK2A2 DYRK1A DYRK2 EIF2B2 EIF2S2 GSK3A GSK3B STX11
Entrez ID 8445 8893
HPRD ID 04606 04898
Ensembl ID ENSG00000127334 ENSG00000145191
Uniprot IDs Q92630 Q13144
PDB IDs 3K2L 3KVW 4AZF 5LXC 5LXD 5ZTN 6HDP 6HDR 6K0J 3JUI 6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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