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BRSK1 and CDC25B
Data Source:
HPRD
(in vitro)
BRSK1
CDC25B
Description
BR serine/threonine kinase 1
cell division cycle 25B
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Synaptic Vesicle
Cell Junction
Presynaptic Active Zone
Distal Axon
Spindle Pole
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Molecular Function
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
ATP Binding
Protein Kinase Binding
Gamma-tubulin Binding
Tau Protein Binding
Tau-protein Kinase Activity
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Kinase Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Mitotic G2 DNA Damage Checkpoint
Neurotransmitter Secretion
Axonogenesis
Associative Learning
Response To UV
Response To Ionizing Radiation
Regulation Of Neuron Projection Development
Peptidyl-serine Phosphorylation
Establishment Of Cell Polarity
Neuron Differentiation
Intracellular Signal Transduction
Cellular Response To Glucose Starvation
Regulation Of Synaptic Plasticity
Regulation Of Axonogenesis
Centrosome Duplication
Microtubule Cytoskeleton Organization Involved In Establishment Of Planar Polarity
Synaptic Vesicle Cycle
Regulation Of Synaptic Vesicle Clustering
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Oocyte Maturation
Protein Phosphorylation
Female Meiosis I
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Cytokinesis
Peptidyl-tyrosine Dephosphorylation
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Mitotic Cell Cycle
Cell Division
Positive Regulation Of G2/MI Transition Of Meiotic Cell Cycle
Pathways
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
L-cysteic acid
Diseases
GWAS
Menarche and menopause (age at onset) (
19448621
)
Menopause (age at onset) (
19448619
26414677
)
Basophil percentage of granulocytes (
27863252
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
8 interacting genes:
BRCA1
CDC25B
CDC25C
HSD17B7
HSPA1A
MAPT
PAK1
WEE1
28 interacting genes:
AATK
AR
AURKA
BRSK1
BRSK2
CDC14A
CDK1
CDK2
CDK5
CHEK1
CREBBP
CSNK2A1
CSNK2B
ESR1
FHL3
KAT2B
MAPK14
MAPK9
MAPKAPK2
MELK
PGR
PSME3
SFN
YWHAB
YWHAE
YWHAH
YWHAQ
YWHAZ
Entrez ID
84446
994
HPRD ID
12533
00307
Ensembl ID
ENSG00000160469
ENSG00000101224
Uniprot IDs
Q8TDC3
B3KS38
B4DIG0
B4DQZ3
B4DRC3
E1YMX4
G8JLH2
P30305
Q6MZW8
PDB IDs
1CWR
1CWS
1CWT
1QB0
1YM9
1YMD
1YMK
1YML
1YS0
2A2K
2IFD
2IFV
2UZQ
3FQT
3FQU
4WH7
4WH9
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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